Author

K. R. Straatman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:proteomics· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. M. Fry· 2 shared A. Lia· 1 shared A. Santino· 1 shared A. Straube· 1 shared C. A. Moores· 1 shared C. J. Hitchman· 1 shared C. P. Modenutti· 1 shared D. N. Hebert· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

A. M. Fry

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Author profile →

3 papers

Recent·Most cited

Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells

N. L. Hindul, L. R. Abbott, S. M. D. Adan, K. R. Straatman, A. M. Fry, K. Hirota, K. Tanaka

This study shows that endogenous oncogenic KRAS mutations increase cell proliferation and motility in hTERT RPE-1 cells, with differential responses to targeted therapies.

bioRxiv · Sep 8, 2023Cell Biology

Rescue of secretion of a rare-disease associated mis-folded mutant glycoprotein in UGGT1 knock-out mammalian cells

G. Tax, K. P. Guay, T. Solde, C. J. Hitchman, J. C. Hill, S. Vasilievic, A. Lia, C. P. Modenutti, K. R. Straatman, M. Molinari, A. Santino, D. N. Hebert, N. Zitzmann, P. Roversi, M. Trerotola

This study shows that knocking out UGGT1 or UGGT1/2 genes rescues secretion of a misfolded Trop-2 glycoprotein mutant in mammalian cells.

bioRxiv · May 30, 2023 · PreprintCell Biology

Mitotic phosphorylation by Nek6 and Nek7 reduces microtubule affinity of EML4 to alter spindle dynamics and promote chromosome congression

A. M. Fry, R. Adib, J. M. Montgomery, J. Atherton, L. O'Regan, M. Richards, K. R. Straatman, D. Roth, A. Straube, R. Bayliss, C. A. Moores

bioRxiv · Nov 9, 2018Cell Biology