Author

Kendall T. Mesch

National Center for Advancing Translational Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Anton M. SimeonoviD· 1 shared Carlos A. TristaniD· 1 shared Celine Herrera-Garcia· 1 shared Chaitali Sen· 1 shared Christopher A. LeClairiD· 1 shared Claudia A. DoegeiD· 1 shared Daniel F. BennettiD· 1 shared David CastellanoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperDevelopmental Biology

Anton M. SimeonovORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders

Vukasin M. Jovanovic, Narisu Narisu, Lori L. Bonnycastle, David Castellano, Seungmi Ryu, Ravi Tharakan, Kendall T. Mesch, Qiang Chen, F.M. Betül Erol, Hannah J. Glover, Tingfen Yan, Neelam Sinha, Chaitali Sen, Shu Yang, Dvir Blivis, , Carlos A. Tristan

This paper describes a scalable method to differentiate human pluripotent stem cells into hypothalamic arcuate neurons, which can model metabolic and reproductive disorders.

Stem Cell Reports · Jun 11, 2026Peer-reviewedDevelopmental Biology

Lentiviral CRISPRa/i in the adult Prairie Vole Brain: Modulating Neuronal Gene Expression Without DNA Cleavage

Meredith K. Loth, Kendall T. Mesch, Celine Herrera-Garcia, Liza E. Brusman, Zoe R. Donaldson

This paper develops a lentiviral CRISPRa/i system for non-mutagenic gene regulation in prairie voles, demonstrating bidirectional modulation of social behavior-related genes in specific brain regions.

Frontiers in Genome Editing · May 30, 2025Peer-reviewedMolecular Biology