Author

Kian Yousefi

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hani GoodarziiD· 2 shared Aidan F. WintersiD· 1 shared Albertas NavickasiD· 1 shared April PawlukiD· 1 shared Ashir A. BorahiD· 1 shared Bahar Zirak· 1 shared Christina Palka· 1 shared Christopher F CarpenteriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenomics

Hani GoodarziORCID

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2 papers

Recent·Most cited

The adaptive architecture of tRNA dependencies across physiological tumor environments

Siyu Chen, Trey Charbonneau, Kian Yousefi, Bahar Zirak, Sean Lee, Tanvi Joshi, April Pawluk, Vijay Ramani, Hani Goodarzi

The paper maps tRNA dependencies in cancer cells across different environments, finding that tRNA dependencies are environmentally sensitive while some dependencies are shared across cell lines.

bioRxiv · Oct 9, 2026 · PreprintGenomics

A systematic search for RNA structural switches across the human transcriptome

Matvei Khoroshkin, Daniel E. Asarnow, Shaopu Zhou, Albertas Navickas, Aidan F. Winters, Jackson Goudreau, Simon K. Zhou, Johnny X. Yu, Christina Palka, Lisa Fish, Ashir A. Borah, Kian Yousefi, Christopher F Carpenter, Karl Mark Ansel, Yifan Cheng, , Hani Goodarzi

The paper identifies 245 putative RNA structural switches in the human transcriptome using a computational and experimental approach, validates one with DMS-MaPseq and cryo-EM, and shows its regulation by trans factors and nonsense-mediated decay.

Nature Methods · Jul 16, 2024Peer-reviewedSystems Biology