Author

Trey Charbonneau

Arc Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

Hani GoodarziiD· 3 shared Aiden M. Sababi· 1 shared Albertas NavickasiD· 1 shared April PawlukiD· 1 shared Bahar Zirak· 1 shared Bong Gun ChoiiD· 1 shared Bruce CulbertsoniD· 1 shared Hamed Shateri NajafabadiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Hani GoodarziORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The adaptive architecture of tRNA dependencies across physiological tumor environments

Siyu Chen, Trey Charbonneau, Kian Yousefi, Bahar Zirak, Sean Lee, Tanvi Joshi, April Pawluk, Vijay Ramani, Hani Goodarzi

The paper maps tRNA dependencies in cancer cells across different environments, finding that tRNA dependencies are environmentally sensitive while some dependencies are shared across cell lines.

bioRxiv · Oct 9, 2026 · PreprintGenomics

Multiplexed mosaic tumor models reveal natural phenotypic variations in drug response within and between populations

Johnny X. Yu, Jung Min Suh, Katerina D. Popova, Kristle Garcia, Tanvi V. Joshi, Bruce Culbertson, Jessica B. Spinelli, Vishvak Subramanyam, Kevin Lou, Trey Charbonneau, Kevan M. Shokat, Jonathan S. Weissman, Hani Goodarzi

This study uses GENEVA to analyze drug response variations in cancer cells, revealing mitochondrial activation's role in KRAS inhibition and EMT as a resistance mechanism.

Nature Cancer · Feb 24, 2026Peer-reviewedCancer Biology

Decoy-seq unlocks scalable genetic screening for regulatory small noncoding RNAs

Bong Gun Choi, Sushil Sobti, Larisa M. Soto, Trey Charbonneau, Aiden M. Sababi, Albertas Navickas, Hamed Shateri Najafabadi, Hani Goodarzi

Decoy-seq enables single-cell perturbation screening of small noncoding RNAs by using TuD decoys to inhibit smRNAs, revealing their regulatory roles in cancer.

bioRxiv · Jan 25, 2025 · PreprintSystems Biology