S. C. Forster

Disease-specific loss of microbial cross-feeding interactions in the human gut

The paper introduces a Metabolite Exchange Score to quantify microbial cross-feeding interactions in the gut and identifies disease-specific disruptions in these interactions.

Fecal microbial transfer and complex carbohydrates mediate protection against COPD

This study shows that fecal microbial transfer and complex carbohydrates can reduce COPD symptoms in mice and humans, linking gut microbiota to disease progression.

Temperate gut phages are prevalent, diverse, and predominantly inactive

The paper characterizes active temperate gut phages from bacterial isolates, finding most are inactive and their induction is complex and context-dependent.

Functional and taxonomic comparison of mouse and human gut microbiotas using extensive culturing and metagenomics

The paper compares mouse and human gut microbiotas using metagenomics and culturing to identify functional similarities and taxonomic differences.

Novel gut pathobionts confound results in a widely used mouse model of human inflammatory disease

The paper identifies two novel gut bacteria that influence disease variability in a mouse model of inflammatory bowel disease.

Host adaptation in gut Firmicutes is associated with sporulation loss and altered colonisation patterns

The paper shows that loss of sporulation in gut Firmicutes is linked to host adaptation, with non-sporulating bacteria being more abundant but less prevalent globally.

Distinct microbial and immune niches of the human colon

The paper examines microbial and immune cell interactions in the human colon, identifying distinct immune niches and T cell profiles along the colon.