Author

K. R. James

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

S. A. Teichmann· 4 shared R. Elmentaite· 3 shared H. W. King· 2 shared K. B. Meyer· 2 shared K. Nayak· 2 shared K. Polanski· 2 shared K. Roberts· 2 shared K. Saeb-Parsy· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCell Biology

S. A. Teichmann

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Author profile →

4 papers

Recent·Most cited

Cells of the human intestinal tract mapped across space and time

R. Elmentaite, N. Kumasaka, H. W. King, K. Roberts, M. Dabrowska, S. Pritchard, L. Bolt, S. F. Vieira, L. Mamanova, N. Huang, I. Goh Kai'En, E. Stephenson, J. Engelbert, R. A. Botting, A. Fleming, , S. A. Teichmann

The paper maps human intestinal cell lineages across development and disease, identifying new cell types and functions related to inflammation and immunity.

bioRxiv · Apr 7, 2021Cell Biology

Single-cell sequencing of developing human gut reveals transcriptional links to childhood Crohns disease

R. Elmentaite, A. Ross, K. R. James, D. Ortmann, T. Gomes, K. Roberts, K. Nayak, L. Tuck, O. Bayraktar, R. Heuschkel, L. Vallier, S. A. Teichmann, M. Zilbauer

The paper maps the developing human gut at 6-10 weeks post-conception using single-cell sequencing and links fetal transcriptional patterns to childhood Crohn's disease.

bioRxiv · Feb 6, 2020Cell Biology

Distinct microbial and immune niches of the human colon

K. R. James, T. Gomes, R. Elmentaite, N. Kumar, E. L. Gulliver, H. W. King, M. D. Stares, B. R. Bareham, J. R. Ferdinand, V. Petrova, K. Polanski, S. C. Forster, L. B. Jarvis, O. Suchanek, S. Howlett, , S. A. Teichmann

The paper examines microbial and immune cell interactions in the human colon, identifying distinct immune niches and T cell profiles along the colon.

bioRxiv · Dec 12, 2019Immunology

Transcriptome Dynamics Reveals Progressive Transition from Effector to Memory in CD4+ T cells.

M. S. F. Soon, H. J. Lee, J. A. Engel, J. Straube, B. S. Thomas, L. S. Clarke, P. Laohamonthonkul, C. P. S. Pernold, R. N. Haldar, C. G. Williams, L. I. M. Lansink, R. Koufariotis, V. Lakis, S. Wood, X. Chen, , A. Haque

This study uses single-cell RNA-seq and ATAC-seq to show a progressive transition from effector to memory CD4+ T cells during Plasmodium infection, with linear pathways and memory-associated gene expression.

bioRxiv · Jun 19, 2019 · PreprintImmunology