Author

L. Benedetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

D. Temelkovski· 2 shared F. D. Ciccarelli· 2 shared P. De Camilli· 2 shared A. Acha-Sagredo· 1 shared A. Guillen-Samander· 1 shared B. Larijani· 1 shared C. Swanton· 1 shared C. Yau· 1 shared

Activity by Year

2018-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

D. Temelkovski

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Immunogenomic profile of colorectal cancer response to immune checkpoint blockade

M. Bortolomeazzi, M. R. Keddar, L. Montorsi, A. Acha-Sagredo, L. Benedetti, D. Temelkovski, S. Choi, N. Petrov, K. Todd, P. Wai, J. Kohl, T. Denner, E. Nye, R. Goldstone, S. Ward, , F. D. Ciccarelli

This study identifies immunogenomic features predicting response to immune checkpoint blockade in colorectal cancer, showing that high clonality and immune escape mechanisms are more important than mutational burden.

bioRxiv · Dec 15, 2020 · PreprintCancer Biology

Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics

L. Benedetti, J. S. Marvin, H. Falahati, A. Guillen-Samander, L. L. Looger, P. De Camilli

This paper describes the development of enhanced Magnets (eMags) for optogenetic control of subcellular processes without requiring concatemerization or low-temperature preincubation.

bioRxiv · Aug 28, 2020Cell Biology

A numerical study about the flight of the dragonfly: 2D gliding and 3D hovering regimes

L. Benedetti, G. Bianchi, S. Cinquemani, M. Belloli

This paper analyzes dragonfly flight regimes through CFD simulations and BEM theory, showing good agreement between simulated and experimental data for gliding and hovering.

bioRxiv · Mar 6, 2020Bioengineering

Nanoscale subcellular architecture revealed by multicolor 3D salvaged fluorescence imaging

Y. Zhang, L. K. Schroeder, M. D. Lessard, P. Kidd, J. Chung, Y. Song, L. Benedetti, Y. Li, J. Ries, P. De Camilli, J. E. Rothman, D. Baddeley, J. Bewersdorf

This paper introduces a super-resolution microscope that images whole mammalian cells at ~20 nm 3D resolution, revealing complex cellular structures previously only visible via electron microscopy.

bioRxiv · Apr 18, 2019Biophysics

Patient-specific detection of cancer genes reveals recurrently perturbed processes in esophageal adenocarcinoma

T. Mourikis, L. Benedetti, E. Foxall, D. Temelkovski, J. Nulsen, J. Perner, M. Cereda, J. Lagergren, M. Howell, C. Yau, R. Fitzgerald, P. Scaffidi, F. D. Ciccarelli

This study identifies patient-specific cancer genes in esophageal adenocarcinoma using machine learning, revealing recurrent process perturbations that suggest therapeutic targets.

bioRxiv · Oct 17, 2018 · PreprintCancer Biology