Author

L. Berneking

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. Aepfelbacher· 3 shared I. Bekere· 2 shared J. Huang· 2 shared K. Ruckdeschel· 2 shared M. Schnapp· 2 shared A. Grundhoff· 1 shared A. Parret· 1 shared B. B. Aldridge· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

M. Aepfelbacher

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Yersinia effector activates JAK-STAT signaling in human macrophages

L. Berneking, I. Bekere, M. Schnapp, J. Huang, K. Ruckdeschel, M. Aepfelbacher

This study shows YopM activates JAK-STAT signaling in macrophages by promoting Stat3 nuclear translocation, independent of IL-10 or RSK1, thereby increasing IL-10 gene expression.

bioRxiv · May 8, 2023 · PreprintCell Biology

Yersinia remodels epigenetic histone modifications in human macrophages

I. Bekere, J. Huang, M. Schnapp, M. Rudolph, L. Berneking, K. Ruckdeschel, A. Grundhoff, T. Günther, N. Fischer, M. Aepfelbacher

This study shows Yersinia enterocolitica modulates histone modifications in human macrophages to alter gene expression related to immune response and metabolism.

bioRxiv · Sep 7, 2021Microbiology

C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus

L. Paulowski, K. S. H. Beckham, M. D. Johansen, L. Berneking, N. Van, Y. Degefu, S. Staack, F. Vasquez Sotomayor, L. Asar, H. Rohde, B. B. Aldridge, M. Aepfelbacher, A. Parret, M. Wilmanns, L. Kremer, , F. P. Maurer

This study develops a C25-modified rifamycin derivative, 5j, which resists enzymatic inactivation by ArrMab and shows potent antimicrobial activity against M. abscessus in vitro and in macrophages.

bioRxiv · Jul 12, 2021Microbiology