L. D. Peters

Immune engineered extracellular vesicles to modulate T cell activation in the context of type 1 diabetes

This study generates engineered extracellular vesicles to modulate T cell activation in type 1 diabetes by presenting HLA-A2 and costimulatory molecules, showing they can activate or suppress CD8+ T cells depending on PD-L1 presence.

Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T cells

This study shows that IGF1 and IL-2 together expand regulatory T cells more effectively than either alone, through distinct signaling pathways and receptor expression changes.