Author

L. D. Roberts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Chuntharpursat-Bon· 2 shared A. Droop· 1 shared A. J. Davies· 1 shared A. Patel· 1 shared B. Da Silva· 1 shared C. Abbosh· 1 shared C. Konstantinou· 1 shared C. W. Cheng· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

E. Chuntharpursat-Bon

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Author profile →

2 papers

Recent·Most cited

PIEZO1 force sensing controls global lipid homeostasis

L. Lichtenstein, C. W. Cheng, E. L. Evans, H. J. Gaunt, F. Bartoli, E. Chuntharpursat-Bon, S. Patel, C. Konstantinou, S. Futers, M. Reay, G. Parsonage, J. Bertrand-Michel, P. Sukumar, L. D. Roberts, D. J. Beech

This study shows that endothelial PIEZO1 force sensing regulates lipid homeostasis by affecting cholesterol metabolism and excretion, with implications for hyperlipidaemia.

bioRxiv · Jul 23, 2023 · PreprintPhysiology

The small molecule KHS101 induces bioenergetic dysfunction in glioblastoma cells through inhibition of mitochondrial HSPD1

E. S. Polson, V. B. Kuchler, C. Abbosh, E. M. Ross, R. K. Mathew, H. A. Beard, E. Chuntharpursat-Bon, J. Williams, B. Da Silva, H. Shao, A. Patel, A. J. Davies, A. Droop, H. B. S. Griffiths, P. Chumas, , H. Wurdak

The paper shows KHS101 inhibits HSPD1 in glioblastoma cells, causing metabolic dysfunction and tumor growth reduction without affecting normal cells.

bioRxiv · Oct 18, 2017Cancer Biology