Author

L. Dubois

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Bitto· 1 shared A. Blanco-Miguez· 1 shared A. M. Thomas· 1 shared A. Mailyan· 1 shared A. S. Grillo· 1 shared B. M. G. Nguyen· 1 shared C. Huttenhower· 1 shared C. Leoni· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Bitto

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Control of intestinal stemness and cell lineage by histone variant H2A.Z isoforms

J. Rispal, C. Rives, V. Jouffret, C. Leoni, L. Dubois, M. Chevillard-Briet, D. Trouche, F. Escaffit

This study investigates the role of H2A.Z isoforms in intestinal homeostasis, showing they regulate stemness, lineage differentiation, and enterocyte differentiation with opposing effects.

Molecular and Cellular Biology · Aug 18, 2024Peer-reviewedPhysiology

Acarbose suppresses symptoms of mitochondrial disease in a mouse model of Leigh Syndrome

A. Bitto, A. S. Grillo, I. B. Stanaway, B. M. G. Nguyen, K. Ying, H. Tung, K. Smith, N. Tran, G. Velikanje, S. Urfer, J. M. Snyder, E.-B. Kayser, L. Wang, D. L. Smith, J. W. Thompson, , M. Kaeberlein

This study shows acarbose reduces symptoms and improves survival in a mouse model of Leigh Syndrome, independent of mTOR inhibition, and suggests gut microbiome modulation may impact mitochondrial disease.

bioRxiv · Jan 31, 2022 · PreprintBiochemistry

Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3

F. Beghini, L. J. McIver, A. Blanco-Miguez, L. Dubois, F. Asnicar, S. Maharjan, A. Mailyan, A. M. Thomas, P. Manghi, M. Valles-Colomer, G. Weingart, Y. Zhang, M. Zolfo, C. Huttenhower, E. A. Franzosa, N. Segata

The paper introduces bioBakery 3, a set of tools for microbial community analysis, improving taxonomic, functional, and strain-level profiling with applications to CRC and IBD datasets.

bioRxiv · Nov 19, 2020Microbiology