Author

E. A. Franzosa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:metagenomics· 4 Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

C. Huttenhower· 4 shared Y. Zhang· 4 shared A. S. Devlin· 2 shared G. Weingart· 2 shared J. R. Huh· 2 shared L. J. McIver· 2 shared L. Yao· 2 shared S. Bae· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersMicrobiology

C. Huttenhower

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Author profile →

4 papers

Recent·Most cited

{-}Multivariable Association Discovery in Population-scale Meta-omics Studies

H. Mallick, A. Rahnavard, L. J. McIver, S. Ma, Y. Zhang, L. H. Nguyen, T. L. Tickle, G. Weingart, B. Ren, E. H. Schwager, S. Chatterjee, K. N. Thompson, J. E. Wilkinson, A. Subramanian, Y. Lu, , C. Huttenhower

This paper introduces MaAsLin 2, a method for analyzing multivariable associations in microbial multi-omics data, and applies it to reveal new insights into inflammatory bowel disease.

bioRxiv · Jan 20, 2021Microbiology

Human gut bacteria produce TH17-modulating bile acid metabolites

D. Paik, L. Yao, Y. Zhang, S. Bae, G. D. D'Agostino, E. Kim, E. A. Franzosa, J. Avila-Pacheco, J. E. Bisanz, C. K. Rakowski, H. Vlamakis, R. J. Xavier, P. J. Turnbaugh, R. S. Longman, M. R. Krout, , A. S. Devlin

This study identifies human gut bacteria that produce TH17-modulating bile acid metabolites, showing reduced levels in IBD patients.

bioRxiv · Jan 8, 2021 · PreprintImmunology

A Bacterial Bile Acid Metabolite Modulates Treg Activity through the Nuclear Hormone Receptor NR4A1

W. Li, S. Hang, Y. Fang, S. Bae, Y. Zhang, G. Wang, M. D. McCurry, M. Bae, E. A. Franzosa, C. Huttenhower, L. Yao, A. S. Devlin, J. R. Huh

This study identifies a bacterial bile acid metabolite, isoalloLCA, that enhances Treg cell differentiation via NR4A1 and is reduced in inflammatory bowel disease patients.

bioRxiv · Jan 8, 2021Immunology

Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3

F. Beghini, L. J. McIver, A. Blanco-Miguez, L. Dubois, F. Asnicar, S. Maharjan, A. Mailyan, A. M. Thomas, P. Manghi, M. Valles-Colomer, G. Weingart, Y. Zhang, M. Zolfo, C. Huttenhower, E. A. Franzosa, N. Segata

The paper introduces bioBakery 3, a set of tools for microbial community analysis, improving taxonomic, functional, and strain-level profiling with applications to CRC and IBD datasets.

bioRxiv · Nov 19, 2020Microbiology