Author

L. E. Sander

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 6 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:human· 4 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

F. Kurth· 4 shared M. Witzenrath· 4 shared A. D. Gruber· 3 shared C. Drosten· 2 shared D. Vladimirova· 2 shared D. Wendisch· 2 shared F. Klein· 2 shared H. Gruell· 2 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersImmunology

F. Kurth

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Neutralization sensitivity of the SARS-CoV-2 Omicron BA.2.75 sublineage

H. Gruell, K. Vanshylla, P. Tober-Lau, D. Hillus, L. E. Sander, F. Kurth, F. Klein

This study evaluates the neutralization sensitivity of the SARS-CoV-2 BA.2.75 sublineage compared to other variants, finding it less resistant to antibodies than BA.4/5 but more than BA.2.

bioRxiv · Aug 4, 2022 · PreprintImmunology

Delineating antibody escape from Omicron sublineages

H. Gruell, K. Vanshylla, M. Korenkov, P. Tober-Lau, M. Zehner, F. Muenn, H. Janicki, M. Augustin, P. Schommers, L. E. Sander, F. Kurth, C. Kreer, F. Klein

This study evaluates antibody escape from Omicron sublineages by testing serum and monoclonal antibody activity against BA.1, BA.2, BA.2.12.1, and BA.4/5, revealing increased resistance in BA.4/5 and identifying promising neutralizing antibodies.

bioRxiv · Apr 6, 2022 · PreprintImmunology

Single cell RNA-seq uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19

M. Aznaourova, N. Schmerer, H. Janga, Z. Zhang, K. Pauck, J. Hoppe, S. M. Volkers, D. Wendisch, P. Georg, M. Guendisch, E. Mack, C. Skevaki, C. Keller, C. Bauer, W. Bertrams, , L. N. Schulte

The paper identifies PIRAT, a lncRNA regulating monocyte immunity in COVID-19 via PU.1 feedback, and shows its role in alarmin production.

bioRxiv · Nov 5, 2021 · PreprintImmunology

Altered fibrin clot structure contributes to thrombosis risk in severe COVID-19

M. Wygrecka, A. Birnhuber, B. Seeliger, L. Michalick, O. Pak, A.-S. Schultz, F. Schramm, M. Zacharias, G. Gorkiewicz, S. David, T. Welte, J. J. Schmidt, N. Weissmann, R. T. Schermuly, G. Barreto, , K. T. Preissner

The paper shows that altered fibrin clot structure in severe COVID-19 patients contributes to thrombosis risk by forming compact, fibrinolysis-resistant clots.

bioRxiv · Sep 17, 2021Biochemistry

A semisynthetic glycoconjugate provides expanded cross-serotype protection against Streptococcus pneumoniae

P. M. Kaplonek, L. Yao, K. Reppe, F. M. Voss, T. Kohler, F. Ebner, A. Schaefer, U. Blohm, P. Priegue, M. Brautigam, C. L. Pereira, S. G. Parameswarappa, M. Emmadi, P. Menova, M. Witzenrath, , P. H. Seeberger

This paper develops a synthetic glycoconjugate vaccine that combines pneumococcal proteins with a defined oligosaccharide to provide broad protection against multiple serotypes of Streptococcus pneumoniae in animal models.

bioRxiv · Jul 29, 2021Immunology

Longitudinal omics in Syrian hamsters integrated with human data unravel complexity of moderate immune responses to SARS-CoV-2

G. Nouailles, E. Wyler, P. Pennitz, D. Postmus, D. Vladimirova, J. Kazmierski, F. Pott, K. Dietert, M. Mülleder, V. Farztdinov, B. Obermayer, S.-M. Wienhold, S. Andreotti, T. Höfler, B. Sawitzki, , M. Witzenrath

The paper integrates longitudinal omics data from Syrian hamsters with human data to understand immune responses to SARS-CoV-2, identifying key cellular and molecular mechanisms.

bioRxiv · Dec 18, 2020Immunology

A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model

J. Kreye, S. M. Reincke, H.-C. Kornau, E. Sanchez-Sendin, V. M. Corman, H. Liu, M. Yuan, N. C. Wu, X. Zhu, C.-C. D. Lee, J. Trimpert, M. Hoeltje, K. Dietert, L. Stoeffler, N. von Wardenburg, , N. Osterrieder

This study identifies a potent SARS-CoV-2 neutralizing antibody that protects hamsters from infection and lung damage.

bioRxiv · Aug 15, 2020Immunology