Author

L. Guiguettaz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metagenomics· 1

Frequent Co-Authors

C. Dahoui· 2 shared E. Ricci· 2 shared L. Etienne· 2 shared A. Cimarelli· 1 shared A. Lapendry· 1 shared A. Legrand· 1 shared A. Moris· 1 shared A. Samri· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

C. Dahoui

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Metabolism-dependent secondary effect of anti-MAPK cancer therapy on DNA repair

F. Aube, N. Fontrodona, L. Guiguettaz, E. Vallin, A. Lapendry, E. P. Ricci, D. Auboeuf

This study shows that MAPK inhibitors reduce aspartate and glutamate in melanoma cells, leading to DNA repair defects and increased mutations through metabolic adaptation.

bioRxiv · Jun 19, 2023Cancer Biology

The inflammatory and tumor suppressor SAMD9L acts through a Schlafen-like box to restrict HIV and inhibit cell translation in SAAD/ATXPC

A. Legrand, C. Dahoui, C. De La Myre Mory, C. Loyer, K. Noy, L. Guiguettaz, M. Pillon, M. Wcislo, L. Gueguen, A. Cimarelli, M. Mateo, F. Fiorini, E. Ricci, L. Etienne

This paper identifies SAMD9L as an HIV-1 restriction factor that inhibits viral and cellular translation through a Schlafen-like box, with implications for HIV/AIDS and genetic diseases.

bioRxiv · Jan 19, 2023Immunology

Extensive uORF translation from HIV-1 transcripts conditions DDX3 dependency for expression of main ORFs and elicits specific T cell immune responses in infected individuals

E. Labaronne, D. Decimo, L. Bertrand, L. Guiguettaz, T. J. Sohier, D. Cluet, V. Vivet-Boubou, C. Dahoui, P. Francois, I. Hatin, O. Lambotte, A. Samri, B. Autran, L. Etienne, C. Goujon, , E. Ricci

The paper characterizes HIV-1 translational landscape, revealing uORF translation and its role in DDX3 dependency and T cell immune responses.

bioRxiv · Apr 29, 2022Microbiology