Author

L. J. Crofford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Gelbard· 1 shared A. W. Lancaster· 1 shared B. S. Bandhi· 1 shared B. Trindade· 1 shared C. L. Duvall· 1 shared C. Montgomery· 1 shared D. D. Liu· 1 shared D. M. Aronoff· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. Gelbard

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Low Gut Microbial Diversity Augments Estrogen-driven Pulmonary Fibrosis in Female-Predominant Interstitial Lung Disease

O. S. Chioma, E. Mallott, B. S. Bandhi, Z. Wiggins, M. Langford, A. W. Lancaster, A. Gelbard, H. Wu, J. Johnson, L. Lancaster, E. Wilfong, L. J. Crofford, C. Montgomery, L. Van Kaer, S. Bordenstein, , W. Drake

The paper shows that low gut microbial diversity worsens estrogen-driven pulmonary fibrosis in female ILD by linking gut dysbiosis, estrogen, and inflammatory pathways.

bioRxiv · Feb 15, 2023 · PreprintImmunology

Matrix-targeted Nanoparticles for MMP13 RNA Interference Blocks Post-Traumatic Osteoarthritis.

S. K. Bedingfield, F. Yu, D. D. Liu, M. A. Jackson, L. E. Himmel, H. Cho, J. M. Colazo, L. J. Crofford, K. A. Hasty, C. L. Duvall

This paper develops MMP13-targeted nanoparticles for RNA interference to treat post-traumatic osteoarthritis, showing significant reduction in MMP13 expression and cartilage damage in mouse models.

bioRxiv · Jan 30, 2020 · PreprintBioengineering

Nonsteroidal anti-inflammatory drugs alter the microbiota and exacerbate Clostridium difficile colitis while dysregulating the inflammatory response

D. Maseda, J. P. Zackular, B. Trindade, L. Kirk, L. J. Crofford, P. D. Schloss, J. L. Roxas, V. K. Viswanathan, G. Vedantam, L. M. Rogers, M. K. Washington, E. P. Skaar, D. M. Aronoff

This study shows NSAIDs like indomethacin alter gut microbiota and worsen C. difficile colitis by disrupting PG metabolism, epithelial integrity, and immune responses in mice.

bioRxiv · Aug 14, 2018Microbiology