Author

L. L. Rubin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

C. D. Hinojosa· 2 shared D. V. Manatakis· 2 shared E. S. Manolakos· 2 shared I. Pediaditakis· 2 shared K. Karalis· 2 shared K. R. Kodella· 2 shared A. Gravanis· 1 shared A. Ordureau· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

C. D. Hinojosa

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Author profile →

3 papers

Recent·Most cited

Analyzing ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets

M. E. Watts, R. M. Giadone, A. Ordureau, K. M. Holton, J. W. Harper, L. L. Rubin

The paper uses ER stressors in ALS patient-derived motor neurons to identify druggable targets that protect against degeneration.

bioRxiv · Nov 16, 2023Cell Biology

A Microengineered Brain-Chip to Model Neuroinflammation in Humans

I. Pediaditakis, K. R. Kodella, D. V. Manatakis, C. Y. Le, S. Barthakur, A. Sorets, A. Gravanis, L. Ewart, L. L. Rubin, E. S. Manolakos, C. D. Hinojosa, K. Karalis

The paper presents a human Brain-Chip that models neuroinflammation by recapitulating brain cell interactions and BBB function, showing improved complexity and clinical relevance compared to existing models.

bioRxiv · Mar 11, 2022Bioengineering

Modeling Alpha-Synuclein Pathology in a Human Brain-Chip to Assess Blood-Brain Barrier Disruption in Parkinson's Disease

I. Pediaditakis, K. R. Kodella, D. V. Manatakis, C. D. Hinojosa, E. S. Manolakos, L. L. Rubin, G. A. Hamilton, K. Karalis

The paper develops a human Brain-Chip model of Parkinson's disease to study blood-brain barrier disruption and synucleinopathy mechanisms.

bioRxiv · Jul 22, 2020Bioengineering