Author

S. E. Lupold

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

A. M. De Marzo· 3 shared R. Chikarmane· 2 shared S. Yegnasubramanian· 2 shared T. L. DeWeese· 2 shared Y. Zhang· 2 shared A. Archey· 1 shared A. Gupta· 1 shared A. Mishra· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersCancer Biology

A. M. De Marzo

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3 papers

Recent·Most cited

Arrested Agonist Paradigm For Selective Radiosensitization of Prostate Cancer

J. B. Coulter, M. Haffner, Y. Zhang, H. Zhou, M.-T. N. Pham, J. Chen, R. Chikarmane, A. Mishra, M. S. Mehl, S. Kazibwe, K. Choi, A. Archey, S. Valluri, S. E. Lupold, D. Song, , S. Yegnasubramanian

This paper identifies hydroxyflutamide as an AR arrested agonist that induces DNA damage in prostate cancer cells, enabling selective radiosensitization without promoting growth.

bioRxiv · Oct 1, 2023 · PreprintCancer Biology

Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer

M. K. Graham, R. Wang, R. Chikarmane, B. Wodu, A. Vaghasia, A. Gupta, Q. Zheng, J. Hicks, P. Sysa-Shah, X. Pan, N. Castagna, J. Liu, J. Meyers, A. Skaist, Y. Zhang, , S. Yegnasubramanian

This study identifies MYC signaling activation as a common driver of tumor microenvironment alterations in human and murine prostate cancer through single-cell RNA-sequencing and comparative analysis.

bioRxiv · Sep 7, 2023Cancer Biology

Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancer

B. Kumar, A. Z. Rosenberg, S. M. Choi, K. Fox-Talbot, A. M. De Marzo, L. Nonn, W. N. Brennen, L. Marchionni, M. K. Halushka, S. E. Lupold

The paper quantifies miRNA expression in prostate stroma and epithelium, finding cell-type specific patterns and associations with prostate cancer recurrence.

bioRxiv · Jan 20, 2018Cancer Biology