Author

M. K. Halushka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. Z. Rosenberg· 2 shared A. E. Jenike· 1 shared A. J. Fenwick· 1 shared A. M. De Marzo· 1 shared B. Fromm· 1 shared B. Kumar· 1 shared D. A. Kass· 1 shared D. Nissen· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

A. Z. Rosenberg

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Author profile →

4 papers

Recent·Most cited

Right Ventricular Sarcomere Contractile Depression and the Role of Thick Filament Activation in Human Heart Failure with Pulmonary Hypertension

V. Jani, M. I. Aslam, A. J. Fenwick, W. Ma, H. Gong, G. Milburn, D. Nissen, I. M. Cubero Salazar, O. Hanselman, M. Mukherjee, M. K. Halushka, K. B. Margulies, K. Campbell, T. C. Irving, D. A. Kass, S. Hsu

This study identifies contractile deficits in right ventricular myocytes of HFrEF-PH patients, showing reduced calcium-activated tension and altered myosin ATP turnover, with implications for targeted therapies.

bioRxiv · Mar 9, 2023Biophysics

Direct observation of the evolution of cell-type specific microRNA expression signatures supports the hematopoietic origin model of endothelial cells

A. E. Jenike, K. M. Jenike, K. J. Peterson, B. Fromm, M. K. Halushka

The paper directly observes the evolution of a cell-type by tracking Mir-126 microRNA expression from proto-endothelial amoebocytes in tunicates to endothelial cells in vertebrates.

bioRxiv · Nov 23, 2022Cell Biology

TAZ/TEAD complex regulates TGF-β1-mediated fibrosis in iPSC-derived renal organoids

X. Yang, M. Delsante, P. Deneshpajouhnejad, P. Fenaroli, K. P. Mandell, X. Wang, S. Takahashi, M. K. Halushka, J. B. Kopp, M. Levi, A. Z. Rosenberg

This study shows that INT-767 prevents fibrosis in iPSC-derived renal organoids by modulating the TEAD4/TAZ pathway.

bioRxiv · Apr 15, 2021 · PreprintCell Biology

Cell-type specific expression of oncogenic and tumor suppressive microRNAs in the human prostate and prostate cancer

B. Kumar, A. Z. Rosenberg, S. M. Choi, K. Fox-Talbot, A. M. De Marzo, L. Nonn, W. N. Brennen, L. Marchionni, M. K. Halushka, S. E. Lupold

The paper quantifies miRNA expression in prostate stroma and epithelium, finding cell-type specific patterns and associations with prostate cancer recurrence.

bioRxiv · Jan 20, 2018Cancer Biology