Author

L. Racioppi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

D. Mukherjee· 2 shared D. P. McDonnell· 2 shared A. Luz· 1 shared A. Means· 1 shared B. Eduful· 1 shared B. Stork· 1 shared B. York· 1 shared C. Catta-Preta· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

D. Mukherjee

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Author profile →

3 papers

Recent·Most cited

SGC-CAMKK2-1: A chemical probe for CAMKK2

C. I. Wells, Y. Liang, T. L. Pulliam, C. Lin, D. Awad, B. Eduful, S. O Byrne, M. A. Hossain, C. Catta-Preta, P. Zonzini Ramos, O. Gileadi, C. Gileadi, R. M. Counago, B. Stork, C. G. Langendorf, , D. H. Drewry

This paper introduces SGC-CAMKK2-1, a selective chemical probe for CAMKK2, demonstrating its potential as a tool to study the therapeutic benefits of CAMKK2 inhibition.

Cells · Jan 11, 2023Peer-reviewedCancer Biology

Increased CaMKK2 expression is an adaptive response that maintains the fitness of tumor-infiltrating natural killer cells

P. K. Juras, L. Racioppi, D. Mukherjee, S. Artham, X. Gao, L. A. D'Agostino, C.-Y. Chang, D. P. McDonnell

This study shows that CaMKK2 in tumor-infiltrating NK cells suppresses apoptosis and promotes proliferation, with its expression driven by intracellular lactic acid.

bioRxiv · May 18, 2022Cancer Biology

Calcium/Calmodulin Dependent Protein Kinase Kinase 2 Regulates the Expansion of Tumor-induced Myeloid-Derived Suppressor Cells

W. Huang, Y. Liu, A. Luz, M. Berrong, J. Meyer, Y. Zou, E. Swann, P. Sundaramoorthy, Y. Kang, S. Jauhari, W. Lento, N. Chao, L. Racioppi

This study identifies CaMKK2 as a regulator of MDSC expansion, showing its inhibition reduces tumor growth and enhances antitumor immunity.

bioRxiv · Jul 28, 2021Immunology