T. Hirashima

E-cadherin-dependent phosphorylation of EGFR governs a homeostatic feedback loop controlling intercellular junction viscosity and collective migration modes.

Interplay between mechanochemical patterning and glassy dynamics in cellular monolayers

The paper investigates how mechanochemical interactions influence cellular monolayer dynamics, showing that a balance between active forces and mechanochemical couplings leads to spatiotemporal patterns.

Three-dimensional analysis and in vivo imaging for sperm release and transport in the murine seminiferous tubule

This study uses 3D analysis and in vivo imaging to examine sperm movement and transport in murine seminiferous tubules, revealing reversed luminal flow patterns.

Metastatic Single Tumor Cells Evade NK Cell-mediated Killing by Thrombin-mediated Loss of the Activating Ligand CD155/PVR/Necl-5

The paper shows metastatic tumor cells evade NK cell killing by losing CD155/PVR/Necl-5 via thrombin, allowing survival in lung capillaries.

Theory of mechano-chemical patterning and optimal migration in cell monolayers

The paper develops a biophysical theory explaining mechano-chemical patterning in cell monolayers and shows how it optimizes collective migration.

ERK-mediated mechanochemical waves direct collective cell polarization

This study shows that ERK-mediated mechanochemical waves coordinate intercellular signaling to direct collective cell migration through long-range polarity alignment.