Author

L. Vanes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1

Frequent Co-Authors

D. Hayward· 3 shared H. Hartweger· 3 shared J. Biggs O'May· 3 shared L. de Boer· 3 shared V. Tybulewicz· 3 shared R. Koechl· 2 shared A. Griffiths· 1 shared A. Morrell· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersImmunology

D. Hayward

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses

J. Biggs O'May, L. Vanes, L. de Boer, H. Hartweger, S. Kunzelmann, D. Hayward, M. Llorian, D. A. Lewis, R. Koechl, V. Tybulewicz

This study shows that WNK1-dependent water influx is essential for CD4+ T cell proliferation and T cell-dependent antibody responses.

bioRxiv · Mar 16, 2022Immunology

T cell migration requires ion and water influx to regulate actin polymerization

L. de Boer, L. Vanes, S. Melgrati, J. Biggs O'May, D. Hayward, P. Driscoll, J. Day, A. Griffiths, R. Magueta, A. Morrell, J. I. MacRae, R. Koechl, V. Tybulewicz

This study shows that chemokine-induced T cell migration requires water entry at the leading edge to facilitate actin polymerization.

bioRxiv · Mar 16, 2022Immunology

B cell-intrinsic requirement for WNK1 kinase in T cell-dependent antibody responses

D. Hayward, L. Vanes, S. Wissmann, S. Sivapatham, H. Hartweger, J. Biggs O'May, L. De Boer, R. Mitter, R. Kochl, J. V. Stein, V. L. Tybulewicz

This study identifies WNK1 kinase as essential for T-dependent antibody responses by regulating B cell migration, adhesion, and activation.

bioRxiv · Sep 9, 2021 · PreprintImmunology

Critical role of WNK1 in MYC-dependent early thymocyte development

R. Köchl, L. Vanes, M. Llorian Sopena, P. Chakravarty, H. Hartweger, K. Fountain, A. White, J. Cowan, G. Anderson, V. Tybulewicz

This study identifies WNK1 as essential for thymocyte development by regulating ion homeostasis and MYC expression during the transition from double negative to double positive thymocytes.

bioRxiv · Jun 11, 2020Immunology