Author

L. de Boer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biophysics· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. Hayward· 3 shared J. Biggs O'May· 3 shared L. Vanes· 3 shared H. Hartweger· 2 shared R. Koechl· 2 shared V. Tybulewicz· 2 shared A. Arora· 1 shared A. Griffiths· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

D. Hayward

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Plasma membrane order maps functional diversity in immune cells

L. A. Andronico, C. O. Gurdap, A. Arora, F. Ragaller, P. A. Sandoz, Y. Jiang, S. Giatrellis, L. de Boer, V. Carannante, S. Iskrak, J. Mikes, M. Buggert, A. Osterborg, B. Onfelt, A. S. Klymchenko, , E. Sezgin

The paper identifies immune cell subsets with distinct functional behaviors based on plasma membrane order using biophysical profiling and transcriptome analysis.

bioRxiv · Jan 15, 2024Biophysics

WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses

J. Biggs O'May, L. Vanes, L. de Boer, H. Hartweger, S. Kunzelmann, D. Hayward, M. Llorian, D. A. Lewis, R. Koechl, V. Tybulewicz

This study shows that WNK1-dependent water influx is essential for CD4+ T cell proliferation and T cell-dependent antibody responses.

bioRxiv · Mar 16, 2022Immunology

T cell migration requires ion and water influx to regulate actin polymerization

L. de Boer, L. Vanes, S. Melgrati, J. Biggs O'May, D. Hayward, P. Driscoll, J. Day, A. Griffiths, R. Magueta, A. Morrell, J. I. MacRae, R. Koechl, V. Tybulewicz

This study shows that chemokine-induced T cell migration requires water entry at the leading edge to facilitate actin polymerization.

bioRxiv · Mar 16, 2022Immunology

B cell-intrinsic requirement for WNK1 kinase in T cell-dependent antibody responses

D. Hayward, L. Vanes, S. Wissmann, S. Sivapatham, H. Hartweger, J. Biggs O'May, L. De Boer, R. Mitter, R. Kochl, J. V. Stein, V. L. Tybulewicz

This study identifies WNK1 kinase as essential for T-dependent antibody responses by regulating B cell migration, adhesion, and activation.

bioRxiv · Sep 9, 2021 · PreprintImmunology

Plant trait heterosis is quantitatively associated with expression heterosis of plastid ribosomal proteins

D. Birdseye, L. De Boer, Z. Shen, H. Bai, P. Zhou, E. A. Schmelz, N. M. Springer, S. Briggs

This study identifies chloroplast ribosomal protein expression heterosis as a quantitative predictor of plant height heterosis in maize hybrids.

bioRxiv · Feb 16, 2021 · PreprintPlant Biology