Author

V. Tybulewicz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cancer & tumor microenvironment· 1 Assay:CITE-seq· 1

Frequent Co-Authors

L. Vanes· 3 shared D. Hayward· 2 shared H. Hartweger· 2 shared J. Biggs O'May· 2 shared L. de Boer· 2 shared R. Koechl· 2 shared A. E. Hauser· 1 shared A. Griffiths· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

L. Vanes

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses

J. Biggs O'May, L. Vanes, L. de Boer, H. Hartweger, S. Kunzelmann, D. Hayward, M. Llorian, D. A. Lewis, R. Koechl, V. Tybulewicz

This study shows that WNK1-dependent water influx is essential for CD4+ T cell proliferation and T cell-dependent antibody responses.

bioRxiv · Mar 16, 2022Immunology

T cell migration requires ion and water influx to regulate actin polymerization

L. de Boer, L. Vanes, S. Melgrati, J. Biggs O'May, D. Hayward, P. Driscoll, J. Day, A. Griffiths, R. Magueta, A. Morrell, J. I. MacRae, R. Koechl, V. Tybulewicz

This study shows that chemokine-induced T cell migration requires water entry at the leading edge to facilitate actin polymerization.

bioRxiv · Mar 16, 2022Immunology

Memory-like B cells emerging from germinal centres recycle through the subcapsular sinus

Y. Zhang, L. Garcia-Ibanez, C. Ulbricht, L. S. C. Lok, T. W. Dennison, J. R. Ferdinand, J. Mueller-Winkler, C. J. M. Burnett, J. C. Yam-Puc, L. Zhang, G. Brown, V. Tybulewicz, A. Rot, A. E. Hauser, M. R. Clatworthy, K.-M. Toellner

The paper tracks B cells exiting germinal centers and shows they recycle through the subcapsular sinus, interacting with macrophages and returning to GCs via CCL21 gradients, supporting affinity maturation to antigenic drift.

bioRxiv · Dec 8, 2020 · PreprintImmunology

Critical role of WNK1 in MYC-dependent early thymocyte development

R. Köchl, L. Vanes, M. Llorian Sopena, P. Chakravarty, H. Hartweger, K. Fountain, A. White, J. Cowan, G. Anderson, V. Tybulewicz

This study identifies WNK1 as essential for thymocyte development by regulating ion homeostasis and MYC expression during the transition from double negative to double positive thymocytes.

bioRxiv · Jun 11, 2020Immunology

Plasmodium-specific atypical memory B cells are not part of the long-lived memory response

D. Perez-Mazliah, P. J. Gardner, E. Schweighoffer, S. McLaughlin, C. Hosking, I. Tumwine, R. S. Davis, A. J. Potocnik, V. Tybulewicz, j. langhorne

The paper shows Plasmodium-specific atypical memory B cells are short-lived and disappear after infection resolution, not part of the long-lived memory response.

bioRxiv · Jun 22, 2018Microbiology