Author

L. Weng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1

Frequent Co-Authors

A. Enomoto· 1 shared A. Masamune· 1 shared B. Aguilar· 1 shared B. Badie· 1 shared B. M. Burkel· 1 shared C. A. Pendexter· 1 shared C. Chu· 1 shared C. E. Brown· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Enomoto

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single-cell profiling reveals the intratumor heterogeneity and immunosuppressive microenvironment in cervical adenocarcinoma

Y. Peng, J. Yang, J. Ao, Y. Li, J. Shen, X. He, D. Tang, C. Chu, C. Liu, L. Weng

This study uses single-cell RNA sequencing to identify unique cell clusters and immunosuppressive features in cervical adenocarcinoma compared to squamous cell carcinoma.

eLife · Mar 11, 2025Peer-reviewedCancer Biology

CAR T cell therapy drives endogenous locoregional T cell dynamics in a responding patient with glioblastoma

V. D. Jonsson, R. Ng, N. Dullerud, R. A. Wong, J. Hibbard, D. Wang, B. Aguilar, R. Starr, L. Weng, D. Alizadeh, S. Forman, B. Badie, C. E. Brown

This study tracks T cell dynamics in a glioblastoma patient undergoing CAR T cell therapy, showing endogenous T cells are activated and contribute to treatment response.

bioRxiv · Sep 22, 2021 · PreprintImmunology

The role of antifreeze glycopeptides (AFGP) and polyvinyl alcohol/polyglycerol (X/Z-1000) cocktails as ice modulators during partial freezing of rat livers.

S. N. Tessier, O. Haque, C. A. Pendexter, S. E. J. Cronin, L. Weng, H. Yeh, J. F. Markmann, M. J. Taylor, G. M. Fahy, M. Toner, K. Uygun

This paper evaluates the effects of AFGP and X/Z-1000 ice modulators on the viability and structure of partially frozen rat livers, finding varying impacts on ATP levels, edema, and endothelial damage.

bioRxiv · Aug 4, 2021 · PreprintPhysiology

Conversion of cancer-associated fibroblasts from pro- to antitumor improves the sensitivity of pancreatic cancer to chemotherapeutics

T. Iida, Y. Mizutani, N. Esaki, S. M. Ponik, B. M. Burkel, L. Weng, K. Kuwata, A. Masamune, S. Ishihara, H. Haga, K. Kataoka, S. Mii, Y. Shiraki, T. Ishikawa, E. Ohno, , A. Enomoto

This study converts pro-tumor CAFs to anti-tumor CAFs using Meflin induction, enhancing PDAC chemosensitivity through improved drug delivery and reduced tissue stiffness.

bioRxiv · Jun 29, 2021 · PreprintCancer Biology