Author

K. Kataoka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 2 Bioengineering· 2 Animal Behavior & Cognition· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 4 Research Focus:drug response / drug discovery· 4 Organism:mouse· 4 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2

Frequent Co-Authors

A. Miyashita· 2 shared K. Sekimizu· 2 shared M. Takahashi· 2 shared S. Abbasi· 2 shared S. Ogawa· 2 shared S. Uchida· 2 shared A. A. Ogasawara· 1 shared A. Barreto-Galvez· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersBiochemistry

A. Miyashita

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

DeepLabCut-based Behavioural and Posture Analysis in a Cricket

S. Hayakawa, K. Kataoka, M. Yamamoto, T. Asahi, T. Suzuki

This paper develops a system using DeepLabCut to analyze cricket behavior and posture, revealing diurnal rhythms in locomotion, feeding, and sleep-like states without human bias or physical tagging.

bioRxiv · Nov 14, 2023 · PreprintAnimal Behavior & Cognition

Acetyl transferase EP300 deficiency leads to chronic replication stress mediated by defective fork protection at stalled replication forks

A. Barreto-Galvez, M. Niljikar, J. Gagliardi, R. Zhang, A. Juwarwala, A. Pradeep, V. Kumar, P. Tiwari, A. Shaikh, K. Sharma, J. Gerhardt, J. Cao, K. Kataoka, A. Durbin, J. Qi, , A. Madireddy

This paper shows that EP300 deficiency causes chronic replication stress and genomic instability in ATLL cells by impairing fork protection and leading to DNA damage and mitotic defects.

bioRxiv · Apr 29, 2023 · PreprintCancer Biology

Jet injection potentiates naked mRNA SARS-CoV-2 vaccine in mice and non-human primates by adding physical stress to the skin

S. Abbasi, M. Matsui-Masai, F. Yasui, A. Hayashi, T. Tockary, S. Akinaga, M. Kohara, K. Kataoka, S. Uchida

This study shows that jet injection improves naked mRNA vaccine efficacy in mice and non-human primates by enhancing delivery and immune response without systemic inflammation.

bioRxiv · Feb 27, 2023 · PreprintBioengineering

Aberrant MYCN expression drives oncogenic hijacking of EZH2 as a transcriptional activator in peripheral T cell lymphoma

M. Vanden Bempt, K. Debackere, S. Demeyer, Q. Van Thillo, N. Meeuws, S. Provost, N. Mentens, K. Jacobs, O. Gielen, D. Nittner, S. Ogawa, K. Kataoka, C. Graux, T. Tousseyn, J. Cools, D. Dierickx

The paper identifies MYCN overexpression in PTCL and shows EZH2 as a transcriptional co-factor for MYCN-driven gene activation, with therapeutic implications for HDAC inhibitors.

bioRxiv · Mar 31, 2022Cancer Biology

Comb-structured mRNA vaccine tethered with short double-stranded RNA adjuvants maximizes cellular immunity for cancer treatment.

T. A. Tockary, S. Abbasi, M. Masai, N. Yoshinaga, S. Fukushima, K. Kataoka, S. Uchida

This paper develops an mRNA vaccine platform that integrates immunostimulatory dsRNA into antigen-encoding mRNA to enhance cancer immunotherapy, showing effective activation of dendritic cells and therapeutic effects in mouse models.

bioRxiv · Jan 18, 2022Bioengineering

Conversion of cancer-associated fibroblasts from pro- to antitumor improves the sensitivity of pancreatic cancer to chemotherapeutics

T. Iida, Y. Mizutani, N. Esaki, S. M. Ponik, B. M. Burkel, L. Weng, K. Kuwata, A. Masamune, S. Ishihara, H. Haga, K. Kataoka, S. Mii, Y. Shiraki, T. Ishikawa, E. Ohno, , A. Enomoto

This study converts pro-tumor CAFs to anti-tumor CAFs using Meflin induction, enhancing PDAC chemosensitivity through improved drug delivery and reduced tissue stiffness.

bioRxiv · Jun 29, 2021 · PreprintCancer Biology

Purification of immunostimulatory glucose homopolymer from broccoli (Brassica oleracea var. italica)

A. Miyashita, K. Kataoka, T. Tsuchida, A. A. Ogasawara, H. Hamamoto, M. Takahashi, K. Sekimizu

The paper isolates and characterizes a glucose homopolymer from broccoli with immunostimulatory effects in both arthropod and mammalian systems.

bioRxiv · May 26, 2021 · PreprintBiochemistry

Activation of innate immunity by neutral polysaccharides from broccoli buds

A. Miyashita, K. Kataoka, K. Sekimizu

This study identifies neutral polysaccharides from broccoli buds as potent immunostimulators, showing stronger activity than acidic polysaccharides in a silkworm muscle contraction assay.

bioRxiv · Mar 10, 2021 · PreprintBiochemistry

Decreased RORC expression and downstream signaling in HTLV-1-associated Adult T-cell Lymphoma/Leukemia uncovers an antiproliferative IL17 link: a potential target for immunotherapy?

K. Subramanian, T. Dierckx, R. Khouri, S. M. Menzes, L. Farre, A. Bittencourt, K. Kataoka, S. Ogawa, J. Van Weyenbergh

The paper identifies decreased RORC expression and downstream antiproliferative IL17 signaling in ATL, suggesting therapeutic potential for boosting RORC/IL17 signaling.

bioRxiv · May 21, 2018Immunology