R. Ng

Homologies and evolution of male tail characters in rhabditid and diplogastrid nematodes

The paper investigates how developmental events and genetic mechanisms underlie recurrent evolution of male tail characters in nematodes, finding both parallel and convergent evolution patterns.

Myristoylated Neuronal Calcium Sensor-1 captures the ciliary vesicle at distal appendages

This study identifies NCS1 as a key protein recruited by CEP89 to the distal appendage, facilitating ciliary vesicle capture and cilium formation.

In vitro engineering of the lung alveolus

This study develops an in vitro strategy to engineer lung alveoli by coordinating biochemical, cellular, and mechanical cues to differentiate alveolar epithelial cells.

CAR T cell therapy drives endogenous locoregional T cell dynamics in a responding patient with glioblastoma

This study tracks T cell dynamics in a glioblastoma patient undergoing CAR T cell therapy, showing endogenous T cells are activated and contribute to treatment response.

High-speed widefield handheld swept-source OCT angiography with a VCSEL light source

This paper presents a high-speed handheld OCT/OCTA system for retinal imaging in clinical settings, demonstrating its use in neonatal and surgical patients.

Host autophagy mediates organ wasting and nutrient mobilization for tumor growth

The paper shows that host autophagy drives organ wasting and nutrient mobilization to support tumor growth in Drosophila.

Type I interferon responses to ischemic injury begin in the bone marrow of mice and humans and depend on Tet2, Nrf2, and Irf3

The paper shows type I interferon responses to ischemic injury start in the bone marrow of mice and humans, involving Tet2, Nrf2, and Irf3, and identifies ISG scores as a clinical biomarker.

Gut microbiota density influences host physiology and is shaped by host and microbial factors

The paper examines factors influencing gut microbiota density across mammals, disease states, and interventions, finding host and microbial factors shape density and impact health.