Author

L.-W. Guo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Pathology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:rat· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Wang· 4 shared M. Zhang· 3 shared Y. Huang· 3 shared G. Urabe· 2 shared H. Shen· 2 shared J. Li· 2 shared J. Plutzky· 2 shared K. C. Kent· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersPathology

B. Wang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Targeted NAD+ Delivery for Intimal Hyperplasia and Re-endothelialization: A Novel Anti-restenotic Therapy Approach

L. Yin, Y. Tong, Z. H. Islam, K. Zhang, R. Xie, J. Burger, N. Hoyt, E. W. Kent, W. A. Marcum, C. Johnston, R. Kanchetty, Z. Tetz, S. Stanisic, Y. Huang, L.-W. Guo, , B. Wang

This study demonstrates that targeted NAD+ delivery via nanocarriers reduces intimal hyperplasia and promotes endothelial regeneration in a rat model of restenosis.

bioRxiv · Feb 20, 2024 · PreprintPathology

The BD2 domain of BRD4 is a determinant in EndoMT and vein graft neointima formation

M. Zhang, B. Wang, G. Urabe, Y. Huang, J. Plutzky, K. C. Kent, L.-W. Guo

This study identifies the BD2 domain of BRD4 as critical for EndoMT and vein graft neointima formation, suggesting it as a therapeutic target.

Cellular Signalling · Sep 1, 2019Peer-reviewedPathology

BRD2 regulation of sigma-2 receptor expression upon cytosolic cholesterol deprivation

H. Shen, J. Li, X. Xie, H. Yang, M. Zhang, B. Wang, C. Kent, J. Plutzky, L.-W. Guo

This study shows BRD2 and SREBP2 work together to increase sigma-2 receptor expression when cells lack cytosolic cholesterol.

bioRxiv · Aug 28, 2019Biochemistry

A non-canonical role and regulations of polo-like kinase-4 in fibroblast cell-type transition

J. Li, G. Urabe, M. Zhang, Y. Huang, B. Wang, L. Marcho, H. Shen, K. C. Kent, L.-W. Guo

This study identifies a non-canonical role for PLK4 in fibroblast cell-type transition and shows its regulation by BRD4 and PDGFR pathways, suggesting PLK4 inhibition as a potential anti-fibrotic intervention.

bioRxiv · Mar 31, 2019 · PreprintCell Biology