Author

Lars Brautigam

Karolinska Institutet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:zebrafish· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Anikó GöblösiD· 1 shared Anna Anoir AbbasiD· 1 shared Balázs Kis· 1 shared Bendegúz SramkóiD· 1 shared Cecilia Söderberg Nauclér· 1 shared Daniela Hühn· 1 shared David Vı́lcheziD· 1 shared Dhifaf SarhaniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Anikó GöblösORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Advancing Adoptive Cell Therapy: Optimized Expansion of Adaptive NK Cells for Solid Tumors

Nerea Martín Almazán, Sara Roman, Yizhe Sun, Lars Brautigam, Mattia Russel Pantalone, Giuseppe Stragliotto, Okan Gultekin, Sahar Saheli, Kaisa Lehti, Cecilia Söderberg Nauclér, Dhifaf Sarhan

This study shows that IL-21 enhances aNK cell expansion and cytotoxicity against tumors, with tumor lysate boosting their efficacy, validated in a zebrafish model.

bioRxiv · Oct 2, 2024 · PreprintImmunology

The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ

Xuexin Li, Ivó H. Hernández, Seda Koyuncu, Balázs Kis, Maria Häggblad, Louise Lidemalm, Anna Anoir Abbas, Bendegúz Sramkó, Anikó Göblös, Lars Brautigam, José J. Lucas, Jordi Carreras Puigvert, Daniela Hühn, Karolina Pircs, David Vı́lchez, Óscar Fernández-Capetillo

The paper identifies clofazimine as a drug that reduces polyQ toxicity by activating PPARγ, improving mitochondrial function in models of polyQ diseases.

EBioMedicine · May 1, 2024Peer-reviewedNeuroscience