Lawrence Huang

Neuronal cell-type and circuit basis for visual predictive processing

The paper identifies VIP-SST-Pyr microcircuit dynamics in visual predictive processing during voluntary running in mice.

Relationship between simultaneously recorded spiking activity and fluorescence signal in GCaMP6 transgenic mice

The paper characterizes the relationship between spiking activity and fluorescence signals in GCaMP6-expressing neurons, finding GCaMP6s has better single-spike detection than GCaMP6f.

A large-scale, standardized physiological survey reveals higher order coding throughout the mouse visual cortex

The paper presents a large-scale dataset of neural activity in the mouse visual cortex and shows that responses to different stimuli are largely independent, suggesting multi-layer hierarchical computation.

On the correspondence of electrical and optical physiology in in vivo population-scale two-photon calcium imaging.

This study calibrates two-photon calcium imaging to recover action potentials in mice, finding that fluorescence changes are inconsistent for small spike numbers and vary by mouse line.

A suite of transgenic driver and reporter mouse lines with enhanced brain cell type targeting and functionality

The paper introduces a new set of transgenic mouse lines for precise targeting and manipulation of brain cell types, enhancing genetic tools for neuroscience research.