Rylan S. Larsen

Differential encoding of temporal context and expectation under representational drift across hierarchically connected areas

The paper shows that visual areas differentially encode temporal context and expectation in natural scenes, with representational drift observed in lower areas but not higher ones.

Motion/direction-sensitive thalamic neurons project extensively to the middle layers of primary visual cortex

The paper shows motion/direction-sensitive thalamic neurons project more to middle layers of V1 than previously thought, challenging existing views on thalamocortical organization.

The spatial structure of feedforward information in mouse primary visual cortex

The paper maps the functional and structural properties of feedforward projections from the LGN to V1 in mice, revealing differences in receptive fields and depth-dependent biases between location-sensitive and motion-sensitive axons.

Activation of neuromodulatory axon projections in primary visual cortex during periods of locomotion and pupil dilation

The paper observes that cholinergic and noradrenergic axons in the mouse primary visual cortex show increased activity during pupil dilation and locomotion, with fluorescence changes preceding and lasting beyond pupil dilation.

A suite of transgenic driver and reporter mouse lines with enhanced brain cell type targeting and functionality

The paper introduces a new set of transgenic mouse lines for precise targeting and manipulation of brain cell types, enhancing genetic tools for neuroscience research.

Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling

This study shows that axotomy leads to dendritic spine loss and presynaptic hyper-excitability in injured neurons, which can be normalized by exogenous netrin-1.