Ulf Knoblich

Relationship between simultaneously recorded spiking activity and fluorescence signal in GCaMP6 transgenic mice

The paper characterizes the relationship between spiking activity and fluorescence signals in GCaMP6-expressing neurons, finding GCaMP6s has better single-spike detection than GCaMP6f.

A large-scale, standardized physiological survey reveals higher order coding throughout the mouse visual cortex

The paper presents a large-scale dataset of neural activity in the mouse visual cortex and shows that responses to different stimuli are largely independent, suggesting multi-layer hierarchical computation.

On the correspondence of electrical and optical physiology in in vivo population-scale two-photon calcium imaging.

This study calibrates two-photon calcium imaging to recover action potentials in mice, finding that fluorescence changes are inconsistent for small spike numbers and vary by mouse line.

A suite of transgenic driver and reporter mouse lines with enhanced brain cell type targeting and functionality

The paper introduces a new set of transgenic mouse lines for precise targeting and manipulation of brain cell types, enhancing genetic tools for neuroscience research.