Author

Lea Eisenhard

Helmholtz Centre for Infection Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:metagenomics· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Till Robin LeskeriD· 2 shared Till StrowigiD· 2 shared Agnieszka Gaska· 1 shared Aurélie CenieriD· 1 shared Birte Abt· 1 shared Daniela WetzeliD· 1 shared Demian Park· 1 shared Dirk SchlüteriD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

Till Robin LeskerORCID

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Author profile →

3 papers

Recent·Most cited

Metabolites produced by gut bacteria under anoxic conditions drive the suppression of Acinetobacter baumannii

Katrin Anja Winter, Lisa Osbelt, Till Robin Lesker, Marie Wende, Éva d. H. Almási, Lea Eisenhard, Leonard Knegendorf, Birte Abt, Jörg Overmann, Michael Hogardt, Volkhard A. J. Kempf, Dirk Schlüter, Meina Neumann‐Schaal, Till Strowig

The paper shows that gut bacteria like Klebsiella oxytoca, under anoxic conditions, suppress Acinetobacter baumannii through metabolites from specific carbohydrates like maltose.

bioRxiv · Sep 29, 2025 · PreprintMicrobiology

Gene-centric metagenomic analyses reveal microbiome functional insights into diseases

Shen Jin, Aurélie Cenier, Lea Eisenhard, Emilio García Ríos, Daniela Wetzel, Woo Young Cho, Till Robin Lesker, Tobias Eisen, Svenja Weißenberger, Agnieszka Gaska, Tingting Zheng, Marilena Stamouli, Merianne Mohamad, SUDIP KUMAR DAS, Vishal Patel, , Melanie Schirmer

The paper develops MetaGEAR, a gene-centric metagenomic analysis framework, to investigate microbiome functionality in diseases and identify disease signature genes and mobile genetic elements.

bioRxiv · Sep 29, 2025 · PreprintMicrobiology

Rapid Directed Molecular Evolution of Fluorescent Proteins in Mammalian Cells

Siranush Babakhanova, Erica Eunjung Jung, Kazuhiko Namikawa, Hanbin Zhang, Yangdong Wang, Oksana M. Subach, Dmitry A. Korzhenevskiy, Tatiana V. Rakitina, Xian Xiao, Wenjing Wang, Jing Shi, Mikhail A. Drobizhev, Demian Park, Lea Eisenhard, Hongyun Tang, , Kiryl D. Piatkevich

This paper describes a method for rapidly optimizing fluorescent proteins in mammalian cells, resulting in enhanced near-infrared fluorescent proteins with improved intracellular brightness and multicolor imaging capabilities.

Protein Science · Dec 16, 2021Peer-reviewedMolecular Biology