Chlamydial Histones Control Developmental Fitness in the Next Infection Cycle
Yuxuan Wang, M. L. Pan, Temitope V. Coker, Jing Wang, Lingling Wang, Guangming Zhong, Huizhou Fan
This study shows that chlamydial histones HctA and HctB are essential for transgenerational developmental fitness, as their deficiency during EB maturation impairs subsequent infection cycles.
bioRxiv · Feb 11, 2026 · PreprintMicrobiology