Author

Lisa Fol

Institute of Molecular Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jan PadekeniD· 2 shared Alexander Schäffer· 1 shared Angelique Schönefeld· 1 shared Ashley WesterbackiD· 1 shared Borhane GuezgueziD· 1 shared Catherine WölfeliD· 1 shared Christoph PlassiD· 1 shared Clarissa Feuerstein-AkgoziD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Jan PadekenORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

DNMT/G9a Complex Inhibition Uncovers Epigenetic Vulnerabilities and Induces IFN-Response in Acute Myeloid Leukemia

Angelique Schönefeld, Costanza Zanetti, Eric C. Schmitt, Kevin Woods, Ashley Westerback, Sidney M. Mitsch, Frank Rühle, Simge Kelekçi, Lisa Fol, Viral Shah, Miriam Sanchez-Saez, Sophia Thevissen, Alexander Schäffer, Ulrike Regina Schmits, Daniel Sasca, , Borhane Guezguez

This study shows that inhibiting the DNMT/G9a complex targets specific epigenetic vulnerabilities in AML, inducing an IFN response and improving therapeutic outcomes.

bioRxiv · Dec 11, 2024 · PreprintCancer Biology

HPL-2/HP1 and MET-2/SETDB1 bind distinct co-factors that promote heterochromatic foci, gene repression and organogenesis independently of H3K9 methylation

Colin E. Delaney, Lisa Fol, Jia Emil You, Stefan B. Gruenewald, Eugenio Ferrario, Susan M. Gasser, Martin M. Moeckel, Lukas Stelzl, Jan Padeken, Susan E. Mango

The paper shows HPL-2 and MET-2 function in parallel H3K9me-independent pathways for gene repression and organogenesis, using distinct co-factors.

bioRxiv · Sep 29, 2024 · PreprintMolecular Biology