Author

M. B. Ginzberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 4

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 2 Organism:C. elegans· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

R. Kafri· 4 shared N. Patel· 3 shared C. Tan· 2 shared M. W. Kirschner· 2 shared N. Chang· 2 shared S. Liu· 2 shared Y. Wang· 2 shared A. Hilfinger· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersCell Biology

R. Kafri

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4 papers

Recent·Most cited

Oversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis

S. Liu, C. Tan, C. Melo-Gavin, M. B. Ginzberg, R. Blutrich, N. Patel, M. Rape, K. G. Mark, R. Kafri

The paper shows oversized cells increase proteasome-mediated protein degradation to maintain size homeostasis by reducing growth efficiency.

bioRxiv · Nov 9, 2021Cell Biology

Cell size homeostasis is maintained by a circuitry involving a CDK4-determined target size that programs the cell size-dependent activation of p38

C. Tan, M. B. Ginzberg, R. Webster, S. Iyengar, J. Concannon, Y. Wang, D. S. Auld, J. L. Jenkins, H. Rost, A. Hilfinger, B. Derry, N. Patel, R. Kafri

The paper identifies CDK4 as a regulator of cell size target size, distinct from growth-promoting pathways, and proposes a model linking mTORC1, p38, and CDK4 in cell size homeostasis.

bioRxiv · Oct 14, 2020Cell Biology

Cell size sensing in animal cells coordinates growth rates and cell cycle progression to maintain cell size uniformity

M. B. Ginzberg, N. Chang, R. Kafri, M. W. Kirschner

The paper shows cells adjust growth rates and cell cycle progression to maintain uniform size by sensing their own size and modifying growth and division timing.

bioRxiv · Apr 3, 2017Cell Biology

Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length

S. Liu, M. B. Ginzberg, N. Patel, M. Hild, B. Leung, Y.-C. Chen, Z. Li, N. Chang, S. Diena, Y. Wang, W. Trimble, L. Wasserman, J. Jenkins, M. W. Kirschner, R. Kafri

The p38 MAPK pathway coordinates cell growth and cell cycle progression by lengthening G1 in small cells, allowing them more time to grow before their next division.

bioRxiv · Mar 23, 2017Cell Biology