Author

M. C. Chang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Alcala· 1 shared A. Hruby· 1 shared A. K. Boal· 1 shared A. Silakov· 1 shared B. J. Katch· 1 shared C. Krebs· 1 shared C.-N. Shen· 1 shared C.-Y. Lin· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. Alcala

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Investigating impacts of marine sponge derived mycothiazole and its acetylated derivative on mitochondrial function and aging.

N. Dutta, J. A. Gerke, S. F. Ordon, J. D. Morris, A. Hruby, T. C. Torres, S. Shemtov, J. G. Clark, M. C. Chang, H. Shaghasi, M. N. Ray, M. Averbukh, S. Hoang, M. Oorloff, A. Alcala, , R. Higuchi-Sanabria

This study investigates the effects of marine sponge-derived mycothiazole and its acetylated derivative on mitochondrial function and aging using in vitro and in vivo models.

bioRxiv · Nov 27, 2023Cell Biology

Synergistic Binding of the Halide and Cationic Prime Substrate of the L-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States

J. W. Slater, M. E. Neugebauer, M. J. McBride, D. Sil, C.-Y. Lin, B. J. Katch, A. K. Boal, M. C. Chang, A. Silakov, C. Krebs, J. M. Bollinger

This paper investigates the synergistic binding of halide and cationic substrates in the BesD enzyme across different iron states, revealing cooperative interactions and decay pathways.

bioRxiv · May 2, 2023Biochemistry

Manufacturing CD20/CD19-targeted iCasp9 regulatable CAR-TSCM cells using qCART, the Quantum pBac-based CAR-T system

P. S. Chang, Y.-C. Chen, W.-K. Hua, J. C. Hsu, J.-C. Tsai, Y.-W. Huang, Y.-H. Kao, P.-H. Wu, Y.-F. Chang, M. C. Chang, Y. C. Chang, S.-L. Jian, J.-S. Lai, M.-T. Lai, W.-C. Yang, , S. C.-Y. Wu

This paper demonstrates the efficient manufacturing of CD20/CD19 dual-targeted, iCasp9-regulatable CAR-TSCM cells using the virus-free qCART system, showing robust tumor eradication and safety.

bioRxiv · May 3, 2022 · PreprintCancer Biology