M. Ferreira

Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome.

This study combines bulk RNA-Seq datasets to create a transcriptomic landscape of meningiomas, identifies subtypes with distinct biology and prognosis, and provides an interactive tool for outcome prediction.

tRNASer overexpression induces adaptive mutations in NSCLC tumors

This study shows that overexpressing tRNASer in NSCLC tumors increases mutation burden and generates variants that promote proliferation and therapy resistance.

ATG9A regulates dissociation of recycling endosomes from microtubules leading to formation of influenza A virus liquid condensates

This study shows ATG9A facilitates the formation of influenza A virus liquid condensates by removing Rab11a-recycling endosomes from microtubules, enabling their condensation near the ER.

Mucosal administration of anti-bacterial antibody provides long-term cross-protection against Pseudomonas aeruginosa respiratory infection

This study shows that mucosal delivery of anti-bacterial antibodies provides rapid pathogen neutralization and long-term cross-protection against secondary Pseudomonas aeruginosa infections.

Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.

This study shows that PCM1 and centriolar satellites are essential for efficient ciliogenesis by facilitating protein trafficking and remodeling of the mother centriole.

Epithelial-mesenchymal plasticity induced by discontinuous exposure to TGFβ1 promotes tumour growth

The paper shows that discontinuous TGFβ1 exposure induces EMT/MET transitions in EpH4 cells, leading to RE-cells with molecular and functional heterogeneity that promotes tumour growth.

Harbor porpoise losing its edges: genetic time series suggests a rapid population decline in Iberian waters over the last 30 years

The paper analyzes mitochondrial genetic variation in harbor porpoises in Iberia over 30 years, finding a significant decline in genetic diversity, suggesting population decline due to environmental or anthropogenic factors.

Evolutionary history of the porpoises (Phocoenidae) across the speciation continuum: a mitogenome phylogeographic perspective

This study reconstructs the evolutionary history of porpoises using mitochondrial genomes, revealing patterns shaped by Quaternary Glaciations and highlighting conservation implications.