Author

M. Gonzales

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1

Frequent Co-Authors

J. Taft· 2 shared K. Niazi· 2 shared M. Martin-Fernandez· 2 shared P. R. Spilman· 2 shared P. Soon-Shiong· 2 shared S. Rabizadeh· 2 shared S. Tanaka· 2 shared W. Higashide· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

J. Taft

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of a short, single site matriglycan that maintains neuromuscular function in the mouse

T. Yang, I. Chandel, M. Gonzales, H. Okuma, S. J. Prouty, S. Zarei, S. Joseph, K. W. Garringer, S. Ocampo Landa, T. Yonekawa, A. S. Walimbe, D. P. Venzke, M. E. Anderson, J. M. Hord, K. P. Campbell

The paper identifies a shorter matriglycan on dystroglycan that maintains neuromuscular function in adult mice and protects skeletal muscle from damage.

bioRxiv · Dec 20, 2023 · PreprintBiochemistry

Sex-specific mechanisms of cerebral microvascular BKCa dysfunction in a mouse model of Alzheimer's disease

J. F. da Silva, F. D. Polk, P. E. Martin, S. H. Thai, A. Savu, M. Gonzales, A. M. Kath, M. T. Gee, P. W. Pires

This study investigates sex-specific mechanisms of BKCa dysfunction in cerebral microvascular function in a 5x-FAD mouse model of Alzheimer's disease, finding differences in BKCa regulation between males and females.

bioRxiv · Jun 6, 2023 · PreprintPhysiology

Rapid Identification of Neutralizing Antibodies against SARS-CoV-2 Variants by mRNA Display

S. Tanaka, C. A. Olson, C. O. Barnes, W. Higashide, M. Gonzales, J. Taft, A. Richardson, M. Martin-Fernandez, D. Bogunovic, P. N. P. Gnanapragasam, P. Bjorkman, P. R. Spilman, K. Niazi, S. Rabizadeh, P. Soon-Shiong

This study uses mRNA display to identify and engineer neutralizing antibodies against SARS-CoV-2 variants, revealing binding modes and demonstrating their effectiveness against mutations in the spike protein.

bioRxiv · Sep 14, 2021Immunology

A recombinant ACE2 Triple Decoy that traps and neutralizes SARS-CoV-2 shows enhanced affinity for highly transmissible SARS-CoV-2 variants

S. Tanaka, G. Nelson, A. Olson, O. Buzko, W. Higashide, A. Shin, M. Gonzales, J. Taft, R. S. Patel, S. Buta, M. Martin-Fernandez, D. S. Bogunovic, P. R. Spilman, K. Niazi, S. Rabizadeh, P. Soon-Shiong

The paper develops an ACE2 Triple Decoy that maintains high affinity for SARS-CoV-2 variants and shows enhanced affinity for specific mutations.

bioRxiv · Mar 9, 2021Bioengineering