Emergence of single cell mechanical behavior and polarity within epithelial monolayers drives collective cell migration
S. Jain, V. Cachoux, G. Sankara, S. de Beco, J. D'Alessandro, V. Cellerin, T. Chen, M. Heuze, P. Marcq, R.-M. Mege, A. Kabla, C. T. Lim, B. Ladoux
This study shows that collective cell migration in epithelial monolayers arises from single-cell polarity signals rather than cell-cell junctions.
bioRxiv · Dec 16, 2019 · PreprintBiophysics