Author

M. J. Boulanger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

R. Ramaswamy· 2 shared A. Acosta-Serrano· 1 shared A. Casas-Sanchez· 1 shared A. K. Snyder· 1 shared A. Kelsen· 1 shared B. Martorelli di Genova· 1 shared C. J. Powell· 1 shared C. Powell· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

R. Ramaswamy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Toxoplasma surface coat protein TgSRS57 (TgSAG3) regulates complement deposition, Factor H recruitment, and promotes parasite persistence

V. Pszenny, P. M. Sikorski, R. Ramaswamy, M. L. Parker, G. Adedoyin, M. J. Boulanger, M. E. Grigg

This study shows TgSRS57 regulates complement deposition and Factor H recruitment on Toxoplasma gondii, promoting parasite persistence and disease tolerance.

bioRxiv · Oct 17, 2022 · PreprintMicrobiology

The class XIV myosin of Toxoplasma gondii, TgMyoA, is druggable in an animal model of infection

A. Kelsen, R. S. Kent, A. K. Snyder, E. Wehri, S. J. Bishop, R. V. Stadler, C. Powell, B. Martorelli di Genova, P. K. Rompikuntal, M. J. Boulanger, D. M. Warshaw, N. J. Westwood, J. Schaletzky, G. E. Ward

This paper identifies KNX-002 as a specific inhibitor of TgMyoA, reducing parasite motility and disease progression in mice.

bioRxiv · Sep 9, 2022 · PreprintMicrobiology

Defining how oncogenic and developmental mutations of PIK3R1 alter the regulation of class IA phosphoinositide 3-kinases

G. L. Dornan, J. T. Stariha, M. K. Rathinawamy, C. J. Powell, M. J. Boulanger, J. E. Burke

This study investigates how mutations in PIK3R1 affect class IA PI3K regulation, finding that oncogenic mutations hyper-activate p110 while developmental mutations reduce RTK sensitivity.

bioRxiv · Jul 16, 2019Biochemistry

The crystal structure and localization of Trypanosoma brucei invariant surface glycoproteins suggest a more permissive VSG coat in the tsetse-transmitted metacyclic stage

A. Casas-Sanchez, S. Perally, R. Ramaswamy, L. R. Haines, C. Rose, C. Yunta, M. Aguilera-Flores, M. J. Lehane, I. C. Almeida, M. J. Boulanger, A. Acosta-Serrano

The paper identifies and characterizes a novel family of invariant surface proteins in the metacyclic stage of Trypanosoma brucei, suggesting a more permissive VSG coat structure that may aid vaccine development.

bioRxiv · Nov 26, 2018 · PreprintMicrobiology