Author

M. J. Podolsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

C. D. Yang· 3 shared K. Atabai· 3 shared R. Datta· 3 shared C. O. Lizama· 2 shared A. H. Beigh· 1 shared B. Kheyfets· 1 shared B. W. Zaro· 1 shared C. Lizama Valenzuela· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersPhysiology

C. D. Yang

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Author profile →

3 papers

Recent·Most cited

MFGE8 inhibits insulin signaling through PTP1B

R. Datta, M. J. Podolsky, C. D. Yang, D. Alba, S. Singh, S. Koliwad, C. O. Lizama, K. Atabai

This study shows MFGE8 inhibits insulin signaling by promoting PTP1B binding to and dephosphorylation of IR{beta}, reducing glucose uptake, and identifies a correlation between serum MFGE8 levels and insulin resistance in humans.

bioRxiv · May 30, 2023 · PreprintPhysiology

Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover

M. J. Podolsky, B. Kheyfets, M. Pandey, A. H. Beigh, C. D. Yang, C. Lizama Valenzuela, R. Datta, P. J. Wolters, M. McManus, L. Qi, K. Atabai

The paper identifies SEL1L as a regulator of collagen turnover through a negative feedback loop, showing its role in limiting collagen accumulation in fibrotic lung disease.

bioRxiv · Jan 13, 2023Cell Biology

MFGE8 links absorption of dietary fatty acids with catabolism of enterocyte lipid stores through HNF4 γ- dependent transcription of CES enzymes

R. Datta, M. A. Gholampour, C. D. Yang, R. Volk, S. Lin, M. J. Podolsky, T. Arnold, F. Rieder, B. W. Zaro, M. Verzi, R. Lehner, N. Abumrad, C. O. Lizama, K. Atabai

This study identifies CES1D as the hydrolase downstream of the MFGE8-vβ5 integrin pathway that regulates catabolism of diet-derived lipid droplets in enterocytes.

bioRxiv · May 16, 2022Physiology