Author

M. Kubitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

W. R. Schief· 3 shared Y. Adachi· 3 shared E. Georgeson· 2 shared O. Kalyuzhniy· 2 shared X. Hu· 2 shared A. B. Ward· 1 shared A. Kaur· 1 shared A. Liguori· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

W. R. Schief

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Author profile →

3 papers

Recent·Most cited

Diverse competitor B cell responses to a germline-targeting priming immunogen in human Ig loci transgenic mice

T. Schiffner, A. Palser, J. G. Jardine, A. Liguori, S. Menis, S. Raemisch, X. Hu, D. W. Kulp, X. Wang, J. K. Diedrich, B. Groschel, O. Kalyuzhniy, R. Tingle, K. Le, E. Georgeson, , W. R. Schief

The paper analyzes B cell responses to a germline-targeting immunogen in human Ig loci transgenic mice, finding diverse non-VRC01-class B cells and competitor B cells recognizing epitopes near the VRC01 epitope.

bioRxiv · Jan 22, 2024 · PreprintImmunology

Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

J. H. Lee, H. J. Sutton, C. A. Cottrell, I. Phung, G. Ozorowski, L. M. Sewall, R. Nedellec, C. Nakao, M. Silva, S. T. Richey, J. L. Torres, W.-H. Lee, E. Georgeson, M. Kubitz, S. Hodges, , S. Crotty

This study shows that germinal center B cells can persist and continue to mutate for 29 weeks after a single immunization, leading to long-lasting antibody responses.

bioRxiv · Dec 20, 2021 · PreprintImmunology

RosettaAntibodyDesign (RAbD): A General Framework for Computational Antibody Design

J. Adolf-Bryfogle, O. Kalyuzhniy, M. Kubitz, B. D. Weitzner, X. Hu, Y. Adachi, W. R. Schief, R. L. Dunbrack

This paper introduces RosettaAntibodyDesign (RAbD), a computational framework for antibody design that improves affinity by redesigning CDRs using structural and sequence-based methods.

bioRxiv · Apr 12, 2018Bioengineering