Author

M. Natsume

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

I. Shiina· 2 shared R. Abe· 2 shared T. Nishida· 2 shared Y. Obata· 2 shared A. Nakano· 1 shared C.-W. Kuo· 1 shared D. Usukura· 1 shared F. Umezawa· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

I. Shiina

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Brefeldin A and M-COPA block the export of RTKs from the endoplasmic reticulum via simultaneous inactivation of ARF1, ARF4, and ARF5

M. Natsume, M. Niwa, S. Ichikawa, T. Okamoto, H. Tsutsui, D. Usukura, T. Murata, R. Abe, M. Shimonaka, T. Nishida, I. Shiina, Y. Obata

This study shows that BFA and M-COPA inhibit RTK export from the ER by inactivating ARF1, ARF4, and ARF5, leading to cancer cell apoptosis.

bioRxiv · Oct 11, 2023Cell Biology

Golgi retention and oncogenic KIT signaling via PLCγ2-PKD2-PI4KIIIβ activation in GIST cells

Y. Obata, K. Kurokawa, T. Tojima, M. Natsume, I. Shiina, T. Takahashi, R. Abe, A. Nakano, T. Nishida

This study identifies the molecular mechanisms by which mutant KIT remains in the Golgi and activates oncogenic signaling in GIST cells.

bioRxiv · Dec 19, 2022 · PreprintCancer Biology

Cancer malignancy is correlated with up-regulation of PCYT2-mediated glycerol phosphate modification of α-dystroglycan

F. Umezawa, M. Natsume, S. Fukusada, K. Nakajima, F. Yamasaki, H. Kawashima, C.-W. Kuo, K.-H. Khoo, T. Shimura, H. Yagi, K. Kato

This study shows that PCYT2-mediated glycerol phosphate modification of α-dystroglycan correlates with cancer progression and promotes cell migration in colorectal cancer.

bioRxiv · Oct 25, 2021 · PreprintBiochemistry