K. Nakajima

Effects of tenascin-C on dental pulp tissue in mice in vivo and on the proliferation and differentiation of dental pulp stem cells into odontoblasts and calcification in vitro

This study examines the effects of tenascin-C on dental pulp tissue in mice and on the differentiation of dental pulp stem cells into odontoblasts, showing reduced inflammation and altered calcification.

Bearskin2 mediates the coordinated secretion of xylogalacturonan and root cap polygalacturonase in Arabidopsis border-like cells

This study shows that BRN2 controls XGA synthesis, which facilitates RCPG export and BLC separation in Arabidopsis.

Three-dimensional morphological analysis revealed the cell patterning bases for the sexual dimorphism development in the liverwort Marchantia polymorpha

The paper uses 3D morphological analysis to show how germline precursor distribution differs between male and female liverworts, driven by MpFGMYB, shaping sexual dimorphism in M. polymorpha.

Disorganization of basement membrane zone architecture causes impaired melanocyte inhabitation in vitiligo

This study identifies disorganized basement membrane zone architecture and MMP2 overexpression in dermal fibroblasts as contributors to melanocyte loss in vitiligo.

Autophagy promotes organelle clearance and organized cell separation of living root cap cells in Arabidopsis thaliana

The paper uses live-cell tracking to show autophagy facilitates organelle rearrangement and organized cell separation in Arabidopsis root cap cells during their functional transition.

Conformational switch in the alpha-synuclein C-terminus domain directs its fibril polymorphs

This study identifies a conformational switch in the alpha-synuclein C-terminus domain that determines fibril polymorphs by altering morphology in response to ionic strength and temperature.

Macromolecular crowding and supersaturation protect hemodialysis patients from the onset of dialysis-related amyloidosis

This study identifies serum albumin concentration as a tertiary risk factor for dialysis-related amyloidosis, showing that maintenance dialysis improves outcomes by increasing serum component concentrations.

Cancer malignancy is correlated with up-regulation of PCYT2-mediated glycerol phosphate modification of α-dystroglycan

This study shows that PCYT2-mediated glycerol phosphate modification of α-dystroglycan correlates with cancer progression and promotes cell migration in colorectal cancer.

Computational capability of ecological dynamics

This paper demonstrates that ecological networks can function as computational resources, introducing 'Ecological Reservoir Computing' to predict future dynamics and emulate nonlinear systems.

Microtubules Promote the Non-cell Autonomy of MicroRNAs by Inhibiting their Cytoplasmic Loading into ARGONAUTE1 in Arabidopsis

The paper shows that microtubules inhibit miR165/6 loading into AGO1 in the cytoplasm, enabling its non-cell autonomous movement in Arabidopsis roots.

In-Depth Characterization and Validation in BRG1-Mutant Lung Cancers Define Novel Catalytic Inhibitors of SWI/SNF Chromatin Remodeling

This study validates novel BRM/BRG1 ATPase inhibitors as chemical probes for SWI/SNF chromatin remodeling and shows their therapeutic potential in BRG1-mut lung cancers.