Author

M. O'Keeffe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Braun· 1 shared A. Garcias Lopez· 1 shared A. Nguyen· 1 shared A. W. Purcell· 1 shared B. Holzmann· 1 shared B. J. Oldfield· 1 shared B. Malissen· 1 shared C. D. Scharer· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperImmunology

A. Braun

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Author profile →

4 papers

Recent·Most cited

A Simple and Rapid Protocol for the Isolation of Murine Bone Marrow Suitable for the Differentiation of Dendritic Cells

R. Song, M. Bafit, K. M. Tullett, P. S. Tan, M. H. Lahoud, M. O'Keeffe, A. W. Purcell, A. Braun

This paper introduces a centrifugation-based method for isolating murine bone marrow to differentiate dendritic cells, which increases cell numbers and yields more type 1 conventional dendritic cells.

bioRxiv · Jan 29, 2024Immunology

Type I interferon dynamics determines memory B cell epigenetic identity in chronic viral infection

L. Cooper, H. Xu, J. Polmear, C. Szeto, E. S. Pang, M. Gupta, J. J. Taylor, K. J. L. Jackson, A. Nguyen, N. La Gruta, L. G. Martelotto, I. A. Parish, M. O'Keeffe, C. D. Scharer, S. Gras, K. L. Good-Jacobson

The paper identifies type I interferon dynamics as a key factor shaping memory B cell development during chronic viral infection and shows that early IFNAR-1 blockade can reverse chromatin changes.

bioRxiv · Mar 2, 2023Immunology

In pursuit of biomarkers for predicting susceptibility to activity-based anorexia (ABA) in adolescent female rats

L. K. Milton, T. Patton, M. O'Keeffe, B. J. Oldfield, C. J. Foldi

This study investigates predictors of susceptibility to activity-based anorexia in adolescent female rats, finding that decision-making and cognitive behavior, rather than baseline locomotion or immune markers, predict vulnerability to weight loss.

bioRxiv · Oct 25, 2021Animal Behavior & Cognition

Migration of intestinal dendritic cell subsets upon intrinsic and extrinsic TLR3 stimulation

A. Garcias Lopez, V. Bekiaris, K. Müller Luda, J. Hütter, K. Getachew Muleta, J. Nakawesi, I. Ulmert, K. Kotarsky, B. Malissen, M. O'Keeffe, B. Holzmann, W. W. Agace, K. Lahl

This study shows that cDC1 and cDC2 subsets migrate similarly in response to TLR3 stimulation, but cDC1 requires type I interferon signaling, highlighting distinct pathways in DC subset migration.

bioRxiv · Nov 14, 2019Immunology