Author

J. Stewart-Ornstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. J. Nelson· 1 shared A. Ku· 1 shared A. Urisman· 1 shared D. A. Malide· 1 shared E. Schollaert· 1 shared F. Seifuddin· 1 shared G. Wang· 1 shared H. Kawagishi· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. J. Nelson

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2 papers

Recent·Most cited

PKC-alpha promotes phosphorylation of KRAS suppressing its oncogenic properties

T. Joglekar, A. Ku, E. Schollaert, Y.-N. Gong, J. Stewart-Ornstein, A. Urisman, M.-T. Wang

This study identifies PKC-alpha as a suppressor of KRAS oncogenic properties through phosphorylation, altering the KRAS-CaM signaling axis in KRAS mutant tumor cells.

bioRxiv · May 24, 2022 · PreprintCancer Biology

Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

R. Houston, S. Sekine, M. J. Calderon, F. Seifuddin, G. Wang, H. Kawagishi, D. A. Malide, Y. Li, M. Gucek, M. Pirooznia, A. J. Nelson, M. P. Stokes, J. Stewart-Ornstein, S. G. Wendell, S. C. Watkins, , Y. Sekine

The paper shows that acetyl-CoA depletion disrupts nucleolar integrity, activates p53 via ribosomal proteins, and is mediated by class IIa HDACs regulating nucleolar phase state.

bioRxiv · Jan 24, 2020Cell Biology