Author

M. J. Calderon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. C. Watkins· 2 shared A. J. Nelson· 1 shared A. R. Cillo· 1 shared A. Somasundaram· 1 shared C. Lampenfeld· 1 shared D. A. A. Vignali· 1 shared D. A. Malide· 1 shared D. P. Normolle· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

S. C. Watkins

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2 papers

Recent·Most cited

Systemic immune dysfunction in cancer patients driven by IL6 and IL8 induction of an inhibitory receptor module in peripheral CD8+ T cells

A. Somasundaram, A. R. Cillo, C. Lampenfeld, L. Oliveri, M. A. Velez, S. Joyce, M. J. Calderon, R. Dadey, D. Rajasundaram, D. P. Normolle, S. C. Watkins, J. G. Herman, J. M. Kirkwood, E. J. Lipson, R. L. Ferris, , D. A. A. Vignali

This study identifies a systemic immune dysfunction in cancer patients driven by IL6 and IL8, leading to CD8+ T cell dysfunction and poor prognosis.

bioRxiv · May 6, 2020 · PreprintCancer Biology

Acetylation-mediated phase control of the nucleolus regulates cellular acetyl-CoA responses

R. Houston, S. Sekine, M. J. Calderon, F. Seifuddin, G. Wang, H. Kawagishi, D. A. Malide, Y. Li, M. Gucek, M. Pirooznia, A. J. Nelson, M. P. Stokes, J. Stewart-Ornstein, S. G. Wendell, S. C. Watkins, , Y. Sekine

The paper shows that acetyl-CoA depletion disrupts nucleolar integrity, activates p53 via ribosomal proteins, and is mediated by class IIa HDACs regulating nucleolar phase state.

bioRxiv · Jan 24, 2020Cell Biology