Author

M. R. Redinbo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

H. Li· 2 shared S. Mani· 2 shared A. Beck· 1 shared A. Chandran· 1 shared A. Gulati· 1 shared A. K. Stewart· 1 shared A. Mani· 1 shared A. Matson· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBiochemistry

H. Li

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Distinct bile salt hydrolase substrate preferences dictate C. difficile pathogenesis

M. H. Foley, M. E. Walker, A. K. Stewart, S. O'Flaherty, E. C. Gentry, G. Allen, S. Patel, M. Pan, V. V. Beaty, M. E. Vanhoy, M. K. Dougherty, S. K. McGill, A. Gulati, P. Dorrestein, E. S. Baker, , C. M. Theriot

The paper identifies bile salt hydrolase (BSH) substrate preferences and shows they inhibit C. difficile by altering bile acid pools in CDI models.

bioRxiv · Mar 24, 2022 · PreprintMicrobiology

Targeting the Pregnane X Receptor Using Microbial Metabolite Mimicry

Z. Dvorak, F. Felix Kopp, C. M. Costello, J. S. Kemp, H. Li, A. Vrzalova, M. Stepankova, I. Iveta Bartonkov, K. Poulikova, B. Vyhlidalova, L. U. Nordstroem, C. Karunaratne, H. Ranhotra, K. S. Mun, A. P. Naren, , R. B. Sartor

This paper develops FKK6, a non-cytotoxic PXR agonist derived from microbial metabolite mimicry, which reduces inflammation and validates the strategy for drug discovery.

bioRxiv · Jan 3, 2020Biochemistry

Inhibition of Microbial Beta-Glucuronidase Does Not Prevent Breast Carcinogenesis in the Polyoma Middle T Mouse

A. Mani, H. Li, S. Evrin, M. R. Redinbo, S. Mani

This study tests if inhibiting microbial beta-glucuronidase prevents breast cancer in MMTV-PyMT mice, finding no significant effect on tumor formation or markers.

bioRxiv · Aug 24, 2019 · PreprintCancer Biology