J. Russell

Lrp10 suppresses IL7R limiting CD8 T cell homeostatic expansion and anti-tumor immunity.

This study identifies Lrp10 as a negative regulator of CD8 T cell homeostasis and tumor resistance by suppressing IL7R levels and enhancing anti-tumor immunity.

Sugar assimilation underlying dietary evolution of Neotropical bats

This study examines sugar assimilation in Neotropical bats, revealing metabolic adaptations to different diets through glucose tolerance tests, genome analysis, and gene expression studies.

Genomic resources for a historical collection of cultivated two-row European spring barley genotypes.

The paper provides genomic and phenotypic data for 209 historical two-row spring barley cultivars, enabling downstream analyses such as GWAS and expression associations.

Barley MLA3 recognizes the host-specificity determinant PWL2 from rice blast (M. oryzae)

The paper shows that the barley NLR Mla3 recognizes the rice blast effector PWL2, conferring resistance in a dosage-dependent manner.

β-Catenin-NFκB-CFTR interactions in cholangiocytes regulate inflammation and fibrosis during ductular reaction

This study identifies a β-catenin-NFκB-CFTR interactome in cholangiocytes that regulates inflammation and fibrosis during ductular reaction in liver disease.

Deploying an in vitro gut model to assay the impact of a mannan-oligosaccharide prebiotic, Bio-Mos(R) on the Atlantic salmon (Salmo salar) gut microbiome.

The paper evaluates the impact of Bio-Mos prebiotic on Atlantic salmon gut microbiome using an in vitro model, showing increased volatile fatty acids and microbial shifts.

Radiation Exposure of the Base of the Heart Accelerates Coronary Atherosclerosis

This study shows that radiation to the base of the heart accelerates coronary atherosclerosis in mice, while apex irradiation does not, suggesting targeted protection of the heart base may reduce radiation-induced atherosclerosis in patients.

Deploying and in vitro gut model to assay the impact of a mannan-oligosaccharide prebiotic, Bio-MOS(R) on the Atlantic salmon (Salmo salar) gut microbiome.

The paper evaluates the impact of Bio-MOS on the Atlantic salmon gut microbiome using an in vitro model, showing increased short-chain fatty acids and microbial shifts.

Development of a three-compartment in vitro simulator of the Atlantic Salmon GI tract and associated microbial communities: SalmoSim

This study develops an in vitro gut model, SalmoSim, for Atlantic salmon to simulate microbial communities and test dietary impacts, finding similar microbial responses to a novel feed in vivo and in vitro.

Nano-Emulsion Adjuvant Enhances Cross-presentation by Lipid Body Formation Independent of Glycolysis

This study shows that the nano-emulsion adjuvant Adjuplex enhances cross-presentation in dendritic cells without requiring glycolysis, relying instead on lipid body formation and ROS.

A footptrint of plant eco-geographic adaptation on the composition of the barley rhizosphere bacterial microbiota

This study shows that eco-geographical adaptation of barley influences its rhizosphere microbiota composition, with domesticated varieties showing stronger genotype effects than wild relatives.

The PMK-3 (p38) Mitochondrial Retrograde Response Functions in Intestinal Cells to Extend Life via the ESCRT Machinery.

This study identifies PMK-3 as a key regulator of life extension in C. elegans following mitochondrial ETC disruption, showing its reliance on ESCRT machinery for cellular signaling.

Dramatic differences in gut bacterial densities help to explain the relationship between diet and habitat in rainforest ants

The paper uses fluorescence microscopy and quantitative PCR to estimate microbial abundance in ants, showing gut bacterial density varies widely and correlates with herbivory in canopy-dwelling ants.