M. Soto

Utility of Cellular Measurements of Non-Specific Endocytosis to Assess the Target-Independent Clearance of Monoclonal Antibodies

The paper develops a cell-based assay to measure non-specific endocytosis of monoclonal antibodies and shows that high non-specific uptake correlates with target-independent clearance and low bioavailability.

Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy

This study shows that aneuploid cancer cells adapt by reducing chromosomal instability and inflammation, with KRAS amplification aiding this adaptation.

Monosomies, trisomies and segmental aneuploidies differentially affect chromosomal stability

This study investigates how different aneuploidies affect chromosomal instability in human cells, finding that trisomies increase segregation errors while monosomies do not induce CIN.

Manufacturing Stable Bacteriophage Powders Using Thin Film Freeze-drying Technology

This paper demonstrates that thin film freeze-drying can produce stable bacteriophage powders suitable for inhalation therapy with minimal titer loss.

M13 phage display to identify a permeating peptide against hyperconcentrated mucin

The paper uses M13 phage display to identify a neutral, hydrophilic peptide that enhances permeation through hyperconcentrated mucin.

Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology

This study evaluates TruTip technology for detecting Mycobacterium tuberculosis in pediatric stool samples, achieving 59% sensitivity and 97% specificity for TB diagnosis.

Mycobacterium tuberculosis detection from oral swabs with Xpert MTB/RIF ULTRA: A pilot study

This study evaluates the sensitivity of detecting Mycobacterium tuberculosis in oral swabs using Xpert MTB/RIF ULTRA, finding 45% sensitivity and 100% specificity compared to sputum liquid culture.